Cortona is an important town that retains all the charm of an ancient village, with its typical alleys and traditional stone buildings. It stands on a hill that offers splendid views over the Val di Chiana.
Of great interest is the sixteenth-century church of Santa Maria delle Grazie al Calcinaio. Among the most notable monuments is the cathedral, Duomo di Giuliano da Sangallo, the Church of St. Francis (12th century), the Sanctuary of Santa Margherita, the Medici Fortress, the Church of San Domenico, and the Palazzo Comunale (13th century).
Two museums bring together a multitude of masterpieces including a splendid Annunciation by Fra Angelico, and works by Luca Signorelli, Berrettini, Pinturicchio and highly important Etruscan, Egyptian, Greek and Roman collections.